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Verruciform xanthoma
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Verruciform xanthoma : ウィキペディア英語版
Verruciform xanthoma
Verruciform xanthoma is an uncommon benign lesion that has a verruciform (wart-like) appearance, but it may appear polypoid, papillomatous, or sessile. Usually found on the oral mucosa of middle-aged persons, verruciform xanthomas have also been reported on the scrotum and penis〔 of middle-aged to elderly Japanese males. While the most common site is the oral mucosa, lesions that occur elsewhere usually arise on the perineum or on the skin with some predisposing factor, such as lymphedema or an epidermal nevus.
==Histology==
A distinguishing feature of verruciform xanthoma is the presence of large numbers of lipid-laden foamy histiocytes〔〔 in the lesion, and essentially limited to, the connective tissue papillae in the lesion. The lesions are solitary, raised, or polypoid with cup-shaped craters filled with parakeratotic cells that blend into keratinocytes of an acanthotic and papillomatous epidermis. There is a neutrophilic infiltrate of varying intensity between plump parakeratotic cells and keratinocytes, near the surface of the epidermis.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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